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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabando, Jorge | CF | Wichita Wind Surge | 23 | 10/31/2008 | Santo Domingo | DOM | Left | Left | 5' 10" | 170 lbs | - |
| Salazar, David | 3B | San Antonio Missions | 24 | 09/09/2007 | Maracay | VEN | Left | Right | 6' 4" | 200 lbs | - |
| Salazar, Esteban | CF | San Antonio Missions | 24 | 05/22/2007 | Santo Domingo | DOM | Switch | Right | 6' 0" | 195 lbs | - |
| Sarabia, Alejandro | 2B | Frisco RoughRiders | 25 | 03/20/2006 | Barahona | DOM | Right | Right | 6' 2" | 190 lbs | - |
| Sarabia, Juan | CF | Northwest Arkansas Naturals | 24 | 04/01/2007 | Cabimas | VEN | Right | Right | 6' 4" | 200 lbs | $700,000 |
| Sauceda, David | RP | San Antonio Missions | 23 | 04/22/2008 | Ciudad Guayana | VEN | Right | Right | 6' 2" | 185 lbs | - |
| Schouten, Josh | 2B | Frisco RoughRiders | 25 | 01/23/2006 | Boston | USA | Right | Right | 5' 10" | 185 lbs | - |
| Scott, Eric | 2B | Corpus Christi Hooks | 24 | 11/12/2007 | Allentown | USA | Right | Right | 6' 3" | 200 lbs | - |
| Scott II, Matt | RF | Free Agent | 26 | 07/17/2005 | Spring | USA | Right | Right | 6' 4" | 205 lbs | - |
| Serrano, Sergio | 1B | Free Agent | 25 | 09/11/2006 | Santo Domingo | DOM | Right | Right | 6' 4" | 200 lbs | - |
| Shenberger, Ben | SP | Amarillo Sod Poodles | 21 | 09/26/2010 | Morada | USA | Right | Right | 6' 7" | 200 lbs | - |
| Shull, Garrett | 2B | Free Agent | 26 | 07/14/2005 | Enid | USA | Switch | Right | 5' 10" | 190 lbs | - |
| Sierra, Ignacio | RP | San Antonio Missions | 23 | 02/27/2008 | Panama | PAN | Switch | Right | 6' 4" | 200 lbs | - |
| Sigmon, Jeff | SP | Northwest Arkansas Naturals | 25 | 11/04/2006 | Lawrence | USA | Switch | Right | 6' 7" | 210 lbs | - |
| Singleton, Ben | RP | Corpus Christi Hooks | 24 | 10/23/2007 | Tinley Park | USA | Right | Right | 6' 4" | 205 lbs | - |
| Slomkowski, Rory | 3B | Northwest Arkansas Naturals | 23 | 02/25/2008 | North Miami Beach | USA | Right | Right | 5' 11" | 190 lbs | - |
| Smith, Hagen | RP | Frisco RoughRiders | 28 | 08/19/2003 | Bullard | USA | Left | Left | 6' 4" | 210 lbs | - |
| Soto, David | SP | Northwest Arkansas Naturals | 23 | 10/07/2008 | San Cristóbal | DOM | Left | Right | 6' 1" | 175 lbs | - |
| Stanfield, Chris | CF | Free Agent | 28 | 07/27/2003 | Tallahassee | USA | Right | Right | 6' 2" | 200 lbs | - |
| Steinert, Jeff | RP | Wichita Wind Surge | 23 | 10/05/2008 | Atlanta | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sulca, Tim | RP | Northwest Arkansas Naturals | 26 | 06/17/2005 | Ferguson | USA | Left | Left | 6' 4" | 200 lbs | - |
| Sutton, Joe | C | Tulsa Drillers | 25 | 10/22/2006 | Glendale | USA | Switch | Right | 6' 2" | 205 lbs | - |
