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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, Mario | CF | Tennesse Smokies | 22 | 09/12/2021 | Bend | USA | Right | Right | 6' 3" | 195 lbs | - |
| Salazar, Willie | 3B | Fayetteville Woodpeckers | 21 | 08/26/2022 | La Vega | DOM | Right | Right | 6' 2" | 190 lbs | - |
| Salguero, Alfredo | SP | Tennesse Smokies | 21 | 12/02/2022 | Santo Domingo | DOM | Right | Right | 6' 8" | 200 lbs | - |
| Salinas, Johnny | RP | Down East Wood Ducks | 24 | 06/02/2019 | Phoenix | USA | Right | Right | 6' 4" | 200 lbs | - |
| Salinas, Juan | RF | Charleston RiverDogs | 21 | 05/10/2022 | Waterloo | USA | Left | Left | 6' 4" | 200 lbs | - |
| Samayoa, Danny | SS | Carolina Mudcats | 20 | 10/16/2023 | San Cristóbal | DOM | Right | Right | 6' 1" | 165 lbs | - |
| Samuels, Ian | 1B | Tennesse Smokies | 20 | 04/14/2023 | Boulder | USA | Right | Right | 6' 5" | 195 lbs | - |
| Sanchez, Alex | 3B | Fredericksburg Nationals | 22 | 10/20/2021 | Yaritagua | VEN | Right | Right | 6' 2" | 185 lbs | - |
| Sanchez, Bobby | RP | Fayetteville Woodpeckers | 20 | 05/01/2023 | Puerto Plata | DOM | Left | Left | 6' 3" | 185 lbs | - |
| Sanchez, Chris | RP | Delmarva Shorebirds | 24 | 05/04/2019 | Peoria | USA | Right | Right | 6' 5" | 200 lbs | - |
| Sanders, Tim | RF | Charleston RiverDogs | 24 | 01/07/2020 | Albuquerque | USA | Left | Left | 6' 0" | 200 lbs | - |
| Santa Cruz, Frank | SP | Free Agent | 24 | 11/29/2019 | Esperanza | DOM | Left | Left | 6' 2" | 185 lbs | - |
| Sarver, Eric | RP | Myrtle Beach Pelicans | 25 | 07/28/2018 | Los Angeles | USA | Right | Right | 6' 3" | 200 lbs | - |
| Saucedo, Juan | 1B | Fayetteville Woodpeckers | 22 | 04/26/2021 | San Pedro de Macorís | DOM | Right | Right | 6' 1" | 200 lbs | - |
| Saunders, Derek | LF | Free Agent | 25 | 09/21/2018 | Los Angeles | USA | Left | Left | 6' 6" | 200 lbs | - |
| Scovell, Tom | 2B | Myrtle Beach Pelicans | 22 | 08/13/2021 | Langford | CAN | Right | Right | 5' 10" | 175 lbs | - |
| Seago, Sean | SP | Fredericksburg Nationals | 22 | 09/22/2021 | El Cajon | USA | Left | Right | 6' 2" | 200 lbs | - |
| Sears, Jeremy | 1B | Augusta GreenJackets | 24 | 12/10/2019 | Somerville | USA | Switch | Right | 6' 8" | 240 lbs | - |
| Segura, Sal | C | Lynchburg Hillcats | 23 | 09/09/2020 | Caripito | VEN | Right | Right | 6' 6" | 215 lbs | - |
| Serrano, David | 1B | Augusta GreenJackets | 25 | 02/05/2019 | Texas City | USA | Right | Right | 6' 1" | 200 lbs | - |
| Shigley, Chris | CF | Fredericksburg Nationals | 20 | 03/23/2023 | Kansas City | USA | Right | Right | 6' 2" | 175 lbs | - |
| Shirley, Chris | 2B | Myrtle Beach Pelicans | 23 | 05/05/2020 | Bakersfield | USA | Right | Right | 6' 4" | 200 lbs | - |
| Shufelt, Jeremy | RP | Salem Red Sox | 24 | 04/27/2019 | Jonesborough | USA | Left | Right | 6' 2" | 200 lbs | - |
| Sierra, Luis | 1B | Free Agent | 25 | 06/03/2018 | Nagua | DOM | Left | Right | 6' 5" | 200 lbs | - |
| Silvers, Joe | 1B | Free Agent | 25 | 12/15/2018 | New Rochelle | USA | Right | Left | 6' 1" | 200 lbs | - |
| Simmons, Tony | RP | Fredericksburg Nationals | 20 | 08/05/2023 | Spring | USA | Right | Right | 6' 1" | 175 lbs | - |
| Smit, Eric | 2B | Carolina Mudcats | 22 | 01/26/2022 | Holden | USA | Right | Right | 6' 4" | 200 lbs | - |
| Soper, Roman | SP | Fredericksburg Nationals | 23 | 12/28/2020 | Portsmouth | USA | Right | Right | 6' 2" | 190 lbs | - |
| Sosa, Bobby | SP | Charleston RiverDogs | 19 | 04/22/2024 | Santo Domingo | DOM | Right | Right | 6' 7" | 200 lbs | - |
| Sotelo, Jonathan | RP | Down East Wood Ducks | 22 | 02/08/2022 | San Pedro de Macorís | DOM | Right | Right | 6' 4" | 195 lbs | - |
| Sotelo, Nelson | 2B | Salem Red Sox | 24 | 02/26/2019 | Montalban | VEN | Right | Right | 6' 1" | 195 lbs | - |
| Soto, Lupe | CF | Lynchburg Hillcats | 25 | 10/06/2018 | Largo | USA | Right | Right | 6' 1" | 205 lbs | - |
| Sprague, Chris | LF | Fayetteville Woodpeckers | 23 | 12/05/2020 | Chicago | USA | Switch | Right | 5' 11" | 190 lbs | - |
| Stahlman, Mike | 2B | Free Agent | 23 | 02/23/2020 | Tucson | USA | Right | Right | 6' 4" | 200 lbs | - |
| Stava, Joe | SP | Myrtle Beach Pelicans | 23 | 08/09/2020 | Round Rock | USA | Left | Left | 6' 0" | 185 lbs | - |
| Stewart, Chris | RP | Charleston RiverDogs | 23 | 02/18/2020 | Houston | USA | Left | Left | 6' 1" | 195 lbs | - |
| Stokes, Dan | SP | Augusta GreenJackets | 21 | 08/12/2022 | Belle Glade | USA | Left | Left | 6' 2" | 175 lbs | - |
| Sullivan, Dave | RP | Carolina Mudcats | 25 | 11/30/2018 | Belmont | USA | Right | Right | 5' 11" | 185 lbs | - |
