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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakamoto, Naganori | RP | Columbia Fireflies | 19 | 02/23/2013 | Sendai | JPN | Left | Left | 5' 10" | 160 lbs | - |
| Salas, Ricky | RP | Delmarva Shorebirds | 25 | 05/30/2007 | Miami Beach | USA | Left | Right | 6' 0" | 190 lbs | - |
| Salazar, Vinny | CL | Columbia Fireflies | 20 | 09/18/2012 | Cumana | VEN | Right | Right | 6' 6" | 195 lbs | - |
| Samuelson, Joe | RP | Fayetteville Woodpeckers | 24 | 12/03/2007 | Sparta | USA | Left | Left | 6' 1" | 200 lbs | - |
| Sanborn, Jeremy | SP | Myrtle Beach Pelicans | 23 | 07/09/2009 | Spanish Lake | USA | Left | Right | 6' 7" | 210 lbs | - |
| Sanchez, Danny | CF | Lynchburg Hillcats | 21 | 11/16/2010 | Lexington | USA | Switch | Right | 5' 11" | 185 lbs | - |
| Sanchez, Mike | RP | Carolina Mudcats | 23 | 05/18/2009 | Maracaibo | VEN | Left | Right | 6' 4" | 200 lbs | - |
| Scalisi, Chris | RP | Myrtle Beach Pelicans | 23 | 03/07/2009 | Castroville | USA | Right | Right | 6' 1" | 190 lbs | - |
| Scarlett, Raheem | SS | Down East Wood Ducks | 25 | 05/02/2007 | Novi | USA | Right | Right | 6' 0" | 190 lbs | - |
| Scheeler, Chris | 1B | Fredericksburg Nationals | 24 | 04/27/2008 | Diboll | USA | Right | Right | 6' 1" | 200 lbs | - |
| Schmidt, Jonathan | 3B | Columbia Fireflies | 26 | 06/12/2006 | Phoenix | USA | Left | Right | 6' 1" | 205 lbs | - |
| Schuster, D.J. | RF | Augusta GreenJackets | 22 | 05/23/2010 | Raymondville | USA | Left | Left | 6' 0" | 170 lbs | - |
| Scott, Victor | CF | Delmarva Shorebirds | 31 | 02/12/2001 | Powder Springs | USA | Left | Left | 5' 11" | 185 lbs | - |
| Seely, Dan | 2B | Salem Red Sox | 22 | 12/03/2009 | Galveston | USA | Right | Right | 6' 2" | 200 lbs | - |
| Serrano, Jose | RF | Salem Red Sox | 23 | 10/05/2009 | Petare | VEN | Left | Left | 6' 3" | 195 lbs | - |
| Serwe, Mike | RF | Columbia Fireflies | 24 | 04/21/2008 | Fremont | USA | Left | Left | 5' 10" | 185 lbs | - |
| Shelton, Jon | RF | Salem Red Sox | 21 | 11/28/2010 | Clifton Park | USA | Right | Right | 6' 2" | 195 lbs | - |
| Shoemake, Ethan | CF | Columbia Fireflies | 22 | 06/25/2010 | Temple Hills | USA | Left | Left | 6' 3" | 180 lbs | - |
| Siller, Alex | 3B | Columbia Fireflies | 18 | 02/17/2014 | Hermosillo | MEX | Right | Right | 6' 2" | 185 lbs | - |
| Silva, Alex | RP | Columbia Fireflies | 20 | 09/23/2012 | Boca Chica | DOM | Left | Left | 6' 4" | 175 lbs | - |
| Sitler, Micah | 1B | Carolina Mudcats | 22 | 07/12/2010 | Indian Head | USA | Left | Left | 6' 6" | 220 lbs | - |
| Smelcer, Kevin | C | Lynchburg Hillcats | 23 | 06/20/2009 | Watertown | USA | Right | Right | 5' 10" | 195 lbs | - |
| Smith, Andy | RP | Charleston RiverDogs | 24 | 01/28/2008 | Boynton Beach | USA | Left | Left | 6' 5" | 205 lbs | - |
| Smith, Chase | SP | Kannapolis Cannon Ballers | 26 | 06/12/2006 | Cartersville | USA | Left | Left | 6' 0" | 190 lbs | - |
| Smith, Omar | RF | Carolina Mudcats | 25 | 10/31/2007 | Coral Gables | USA | Left | Left | 6' 4" | 215 lbs | - |
| Snel, Ricky | RP | Columbia Fireflies | 20 | 08/10/2012 | Willemstad | CUR | Right | Right | 6' 0" | 175 lbs | - |
| Snell, Lebarron | 3B | Fredericksburg Nationals | 23 | 08/23/2009 | Jacksonville | USA | Right | Right | 6' 1" | 195 lbs | - |
| Sosa, Juan | SS | Kannapolis Cannon Ballers | 20 | 11/05/2012 | Valencia | VEN | Right | Right | 5' 10" | 170 lbs | - |
| Sparks, Adan | CF | Delmarva Shorebirds | 24 | 12/06/2007 | Arlington | USA | Left | Left | 6' 0" | 185 lbs | - |
| Srgio, MÃ ximo | LF | Kannapolis Cannon Ballers | 20 | 04/23/2012 | Charallave | VEN | Switch | Right | 6' 2" | 190 lbs | - |
| Starks, Paul | RP | Fredericksburg Nationals | 23 | 10/04/2009 | Minnetonka | USA | Right | Right | 6' 2" | 200 lbs | - |
| Steffens, Mike | CL | Augusta GreenJackets | 19 | 02/07/2013 | Woodridge | USA | Left | Left | 6' 3" | 195 lbs | - |
| Strelioff, Earl | SS | Delmarva Shorebirds | 24 | 06/08/2008 | Sainte-Anne-des-Plaines | CAN | Switch | Right | 6' 2" | 195 lbs | - |
| Sullivan, Jim | 2B | Carolina Mudcats | 23 | 10/15/2009 | Windham | USA | Left | Right | 6' 1" | 175 lbs | - |
| Syslo, Jon | C | Carolina Mudcats | 29 | 03/10/2003 | Newport | USA | Right | Right | 6' 2" | 200 lbs | $570,500 |
