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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salguero, Manny | 2B | Peoria Chiefs | 25 | 10/02/2007 | Landen | USA | Right | Right | 5' 11" | 190 lbs | - |
| Salmeron, Wil | CL | West Michigan Whitecaps | 23 | 05/14/2009 | North Atlanta | USA | Right | Right | 6' 0" | 190 lbs | - |
| Samuels, Joe | RP | Cedar Rapids Kernels | 23 | 12/03/2008 | Webster Groves | USA | Right | Left | 6' 6" | 205 lbs | - |
| Sanchez, Jose | CF | Lansing Lugnuts | 22 | 07/02/2010 | Truckee | USA | Right | Right | 6' 1" | 185 lbs | - |
| Schmenk, Jimmy | SP | Lansing Lugnuts | 24 | 07/12/2008 | Cascade-Fairwood | USA | Left | Left | 6' 4" | 200 lbs | - |
| Segura, Jordan | CF | Beloit Snappers | 21 | 01/26/2011 | Valencia | VEN | Right | Right | 6' 4" | 200 lbs | - |
| Seitzinger, Damian | C | Lake County Captains | 20 | 02/28/2012 | Macon | USA | Right | Right | 6' 5" | 205 lbs | - |
| Sevier, Jared | RF | Peoria Chiefs | 26 | 12/08/2005 | West Bloomfield Township | USA | Left | Left | 5' 10" | 195 lbs | - |
| Shelton, Danny | SP | Great Lakes Loons | 27 | 01/26/2005 | Portsmouth | USA | Right | Right | 5' 10" | 205 lbs | - |
| Shelton, Jim | 3B | West Michigan Whitecaps | 22 | 01/22/2010 | Albert Lea | USA | Left | Right | 6' 0" | 190 lbs | - |
| Shere, Dave | RP | Free Agent | 24 | 03/02/2008 | Oshawa | CAN | Right | Right | 6' 4" | 200 lbs | - |
| Shumate, Jeremy | RP | Wisconsin Timber Rattlers | 25 | 06/02/2007 | Minneapolis | USA | Right | Right | 6' 0" | 195 lbs | - |
| Silva, Eddie | RP | Lansing Lugnuts | 24 | 12/28/2007 | Belvidere | USA | Right | Right | 6' 1" | 195 lbs | - |
| Simeone, Tim | 1B | Fort Wayne TinCaps | 22 | 09/12/2010 | Los Altos | USA | Right | Right | 6' 6" | 230 lbs | - |
| Smith, Mike | CF | Fort Wayne TinCaps | 24 | 08/09/2008 | Chicago | USA | Right | Left | 6' 2" | 200 lbs | - |
| Snavely, Sean | LF | Dayton Dragons | 24 | 08/04/2008 | Glenside | USA | Right | Right | 6' 1" | 205 lbs | - |
| Sokoloff, Jonathan | CF | South Bend Cubs | 26 | 10/22/2006 | North Attleborough | USA | Right | Right | 6' 2" | 200 lbs | - |
| Soto, Tony | 2B | Peoria Chiefs | 25 | 04/29/2007 | San Juan | PUR | Switch | Right | 6' 2" | 200 lbs | - |
| Springer, Josh | C | Lansing Lugnuts | 26 | 10/10/2006 | Paradise | USA | Right | Right | 6' 0" | 210 lbs | - |
| Stephens, Nate | CF | Lansing Lugnuts | 22 | 11/09/2009 | California City | USA | Left | Right | 6' 0" | 185 lbs | - |
| Stinson, Charlie | RP | Dayton Dragons | 23 | 10/23/2009 | Taunton | USA | Right | Right | 5' 11" | 185 lbs | - |
| Stopani, Jose | RF | Fort Wayne TinCaps | 22 | 08/27/2010 | Higüey | DOM | Left | Left | 6' 4" | 205 lbs | - |
| Stroud, Andy | SP | Lake County Captains | 23 | 08/13/2009 | Roseville | USA | Right | Right | 6' 1" | 200 lbs | - |
| Stumpf, Joe | CF | Wisconsin Timber Rattlers | 26 | 09/26/2006 | San Francisco | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sullivan, Tylor | RP | West Michigan Whitecaps | 23 | 07/22/2009 | Washington | USA | Switch | Right | 6' 0" | 185 lbs | - |
| Sumano, Jorge | RP | Fort Wayne TinCaps | 23 | 05/15/2009 | Trujillo | VEN | Right | Right | 6' 4" | 200 lbs | - |
| Supp, Rob | 1B | Wisconsin Timber Rattlers | 26 | 09/15/2006 | Concord | USA | Left | Left | 6' 4" | 215 lbs | - |
| Sutton, Art | SP | Wisconsin Timber Rattlers | 21 | 01/17/2011 | Montgomery | USA | Right | Right | 6' 1" | 190 lbs | - |
| Svikander, Johannes | SP | Lake County Captains | 23 | 10/27/2009 | Yakima | USA | Right | Right | 5' 9" | 170 lbs | - |
| Syme, Eric | RP | Dayton Dragons | 22 | 07/26/2010 | Detroit | USA | Right | Left | 5' 11" | 175 lbs | - |
