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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sadowski, Jeremy | SP | Jersey Shore BlueClaws | 24 | 11/23/2007 | Westminster | USA | Left | Left | 6' 7" | 230 lbs | - |
| Salmans, Ron | 1B | Greensboro Grasshoppers | 23 | 03/07/2009 | East Chicago | USA | Right | Right | 6' 7" | 230 lbs | - |
| Sanborn, Jimmy | RF | Bowling Green Hot Rods | 25 | 12/16/2006 | San Antonio | USA | Left | Left | 6' 2" | 205 lbs | - |
| Sanders, Brayden | RP | Brooklyn Cyclones | 29 | 11/27/2002 | Olive Branch | USA | Left | Right | 5' 10" | 195 lbs | - |
| Sanders, Tony | RF | Greensboro Grasshoppers | 26 | 10/14/2006 | Syracuse | USA | Right | Right | 6' 5" | 205 lbs | - |
| Satterfield, Joe | RF | Asheville Tourists | 21 | 04/12/2011 | Dolan Springs | USA | Left | Left | 6' 7" | 200 lbs | - |
| Schott, Jaelen | C | Hudson Valley Renegades | 22 | 11/25/2009 | Winston-Salem | USA | Right | Right | 6' 0" | 200 lbs | - |
| Schroeder, Bobby | 1B | Greenville Drive | 24 | 07/30/2008 | Baltimore | USA | Right | Right | 6' 2" | 210 lbs | - |
| Scott, Tommy | SP | Wilmington Blue Rocks | 23 | 04/03/2009 | Clearfield | USA | Left | Left | 6' 2" | 200 lbs | - |
| Segura, Tony | SP | Rome Braves | 22 | 05/26/2010 | Caibarién | CUB | Right | Right | 6' 4" | 210 lbs | - |
| Seiter, Pat | RP | Brooklyn Cyclones | 28 | 06/10/2004 | New York | USA | Right | Right | 6' 1" | 205 lbs | - |
| Serrano, Enyer | CF | Brooklyn Cyclones | 28 | 05/14/2004 | Unknown | VEN | Left | Right | 5' 11" | 200 lbs | - |
| Shapen, Blake | SS | Aberdeen Ironbirds | 31 | 01/22/2001 | Shreveport | USA | Right | Right | 6' 1" | 200 lbs | - |
| Shipley, Jarod | SS | Brooklyn Cyclones | 29 | 03/09/2003 | St. Charles | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Sibson, Mike | RP | Wilmington Blue Rocks | 23 | 01/27/2009 | Madison | USA | Right | Right | 6' 2" | 195 lbs | - |
| Simmons, Kendall | 3B | Rome Braves | 32 | 04/11/2000 | Macon | USA | Right | Right | 6' 2" | 200 lbs | - |
| Smith, Geoff | SP | Bowling Green Hot Rods | 22 | 06/30/2010 | Economy | USA | Right | Right | 6' 3" | 205 lbs | - |
| Soto, Daniel | 1B | Greenville Drive | 24 | 11/18/2007 | Soteapan | MEX | Right | Right | 6' 3" | 200 lbs | - |
| Spaid, Tim | SP | Brooklyn Cyclones | 25 | 09/19/2007 | Humble | USA | Right | Right | 6' 6" | 215 lbs | - |
| Spence, Jake | CL | Hickory Crawdads | 25 | 04/20/2007 | Irvine | USA | Right | Right | 6' 7" | 215 lbs | - |
| Spurlock, Sean | CF | Rome Braves | 27 | 03/29/2005 | Hallandale | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sustaita, Gilberto | RP | Wilmington Blue Rocks | 24 | 08/23/2008 | Santiago | DOM | Right | Right | 5' 11" | 185 lbs | - |
