| # | Name | Team | Opp | Date | Score | IP | R | H | HR | BB | K | GS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Lucas Giolito | AZ | NYM | April 29, 2025 | 7-0 | 9.0 | 0 | 1 | 0 | 1 | 13 | 103 |
| 2 | Chris Sale | SEA | KC | July 2, 2025 | 4-0 | 8.2 | 0 | 1 | 0 | 1 | 14 | 102 |
| 3 | Bobby Miller | LAD | ATL | May 4, 2025 | 4-0 | 8.2 | 0 | 2 | 0 | 0 | 12 | 100 |
| 4 | Mitch Keller | STL | WSH | July 8, 2025 | 4-0 | 9.0 | 0 | 3 | 0 | 0 | 11 | 99 |
| 5 | Yu Darvish | BOS | TOR | June 27, 2025 | 4-0 | 9.0 | 0 | 1 | 0 | 1 | 8 | 98 |
| 6 | Nathan Eovaldi | TB | TEX | June 4, 2025 | 9-2 | 8.1 | 0 | 2 | 0 | 0 | 10 | 96 |
| 7 | Max Scherzer | MIA | MIL | July 5, 2025 | 2-0 | 8.0 | 0 | 1 | 0 | 0 | 8 | 94 |
| 8 | Luis Garcia | CIN | SF | March 27, 2025 | 8-2 | 8.0 | 0 | 2 | 0 | 0 | 10 | 94 |
| 9 | Yu Darvish | BOS | NYY | June 15, 2025 | 3-0 | 7.2 | 0 | 2 | 0 | 0 | 11 | 93 |
| 10 | Luis Castillo | SD | PIT | May 3, 2025 | 1-3 | 7.2 | 1 | 2 | 0 | 0 | 14 | 93 |
| 11 | Roki Sasaki | CHC | SF | May 6, 2025 | 4-0 | 8.1 | 0 | 2 | 0 | 2 | 11 | 93 |
| 12 | Tyler Glasnow | LAD | NYY | June 1, 2025 | 10-0 | 8.0 | 0 | 3 | 0 | 0 | 10 | 92 |
| 13 | Tyler Mahle | NYY | PIT | April 4, 2025 | 3-0 | 8.0 | 0 | 2 | 0 | 1 | 10 | 92 |
| 14 | Logan Allen | DET | BOS | May 13, 2025 | 1-0 | 7.2 | 0 | 1 | 0 | 2 | 12 | 92 |
| 15 | Nick Martinez | BAL | NYM | July 9, 2025 | 1-0 | 7.0 | 0 | 2 | 0 | 0 | 13 | 91 |
| 16 | Aaron Nola | AZ | ATL | April 27, 2025 | 8-0 | 8.2 | 0 | 4 | 0 | 2 | 10 | 90 |
| 17 | Shane Bieber | TB | ATL | April 13, 2025 | 13-0 | 7.1 | 0 | 1 | 0 | 1 | 10 | 90 |
| 18 | Andrew Abbott | CWS | TEX | May 23, 2025 | 10-0 | 7.2 | 0 | 2 | 0 | 1 | 10 | 90 |
| 19 | Chris Sale | SEA | TEX | May 2, 2025 | 5-2 | 7.1 | 0 | 1 | 0 | 1 | 10 | 90 |
| 20 | Kyle Wright | COL | NYM | June 7, 2025 | 9-1 | 8.2 | 1 | 5 | 0 | 0 | 10 | 89 |
| 21 | Bryce Elder | LAA | CWS | June 10, 2025 | 2-5 | 8.0 | 0 | 3 | 0 | 1 | 9 | 89 |
| 22 | Spencer Schwellenbach | SEA | LAA | April 9, 2025 | 5-0 | 8.2 | 0 | 5 | 0 | 1 | 9 | 89 |
| 23 | Zack Wheeler | PHI | NYM | June 21, 2025 | 4-0 | 7.1 | 0 | 3 | 0 | 0 | 11 | 89 |
| 24 | Ben Lively | CHC | STL | June 25, 2025 | 2-1 | 8.0 | 0 | 4 | 0 | 0 | 9 | 89 |
| 25 | Patrick Sandoval | HOU | ATL | July 8, 2025 | 12-1 | 8.2 | 1 | 3 | 0 | 1 | 7 | 88 |
| 26 | Logan Gilbert | MIL | CLE | May 12, 2025 | 8-2 | 7.0 | 0 | 3 | 0 | 0 | 12 | 88 |
| 27 | Kolby Allard | KC | PIT | July 9, 2025 | 2-0 | 8.0 | 0 | 2 | 0 | 0 | 4 | 88 |
| 28 | Tarik Skubal | BAL | BOS | May 23, 2025 | 2-3 | 7.0 | 0 | 1 | 0 | 0 | 8 | 88 |
| 29 | Tyler Glasnow | LAD | LAA | July 4, 2025 | 5-1 | 7.2 | 0 | 2 | 0 | 1 | 8 | 88 |
| 30 | Sandy Alcantara | MIL | HOU | April 19, 2025 | 1-0 | 8.0 | 0 | 3 | 0 | 1 | 8 | 88 |