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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Eddowes, Wayne | LF | Wildwood Fishers | 24 | 05/29/2044 | Kansas City | USA | Left | Left | 6' 2" | 200 lbs | - |
| Edwards, Willie | SP | Indianapolis Indians | 16 | 05/11/2053 | Saint-Michel-des-Saints | CAN | Right | Right | 6' 2" | 175 lbs | - |
| Eliades, Kit | SP | Nashville Nightmare | 18 | 09/15/2050 | Lemesos | CYP | Left | Left | 6' 2" | 180 lbs | - |
| Elliott, Joseph | RP | Iowa City Stalkers | 32 | 08/16/2036 | Brownsville-Bawcomville | USA | Right | Right | 6' 6" | 200 lbs | $500,000 |
| Elliott, Thomas | RP | Free Agent | 23 | 12/25/2045 | Melbourne | USA | Left | Left | 6' 5" | 200 lbs | - |
| Elomo, Unto | C | Ypsi Yard Cats | 17 | 07/17/2051 | Äetsä | FIN | Right | Right | 6' 3" | 200 lbs | - |
| Emery, Edgar | SP | Motown Hitmakers | 20 | 05/15/2049 | Bridgenorth-Chemong Park Area | CAN | Left | Left | 6' 2" | 175 lbs | - |
| Encano, Javier | 3B | Free Agent | 16 | 11/15/2052 | Santiago | DOM | Switch | Right | 6' 1" | 185 lbs | - |
| Enríquez, Dale | RP | Indianapolis Indians | 37 | 12/05/2031 | Naranjito | PUR | Left | Left | 6' 4" | 200 lbs | $4,040,000 |
| Enríquez, Rafael | C | Free Agent | 19 | 05/12/2050 | Managua | NCA | Switch | Right | 6' 2" | 200 lbs | - |
| Erickson, Kennan | SP | Letterkenny Shamrocks | 16 | 12/02/2052 | Toronto | CAN | Left | Left | 6' 1" | 175 lbs | - |
| Escamilla, Alejandro | 3B | Columbus Red Birds | 23 | 10/05/2045 | Mexico City | MEX | Left | Right | 6' 4" | 200 lbs | $500,000 |
| Escamilla, Félix | SP | Grand Rapids Growlers | 19 | 01/20/2050 | Colón | PAN | Left | Left | 6' 0" | 170 lbs | - |
| Escarra, Juan | 3B | Motown Hitmakers | 19 | 10/02/2049 | Bohechío | DOM | Left | Right | 6' 1" | 200 lbs | - |
| Escobar, Carlos | RP | Free Agent | 17 | 12/16/2051 | Santo Domingo | DOM | Right | Right | 6' 0" | 165 lbs | - |
| Escobar, Claudio | RP | Great Black Swamp Mud Hens | 27 | 03/21/2042 | Guaimaro | CUB | Left | Left | 6' 0" | 190 lbs | $500,000 |
| Escobar, Ernesto | 3B | Asheville Boomsticks | 18 | 07/17/2050 | San Bartolo | MEX | Switch | Right | 6' 5" | 205 lbs | - |
| Escobedo, Freddy | SP | Columbus Red Birds | 17 | 07/03/2051 | Nueva Guinea | NCA | Right | Right | 5' 11" | 165 lbs | - |
| Escobedo, Joey | SP | Free Agent | 17 | 09/13/2051 | San Juan | PUR | Right | Right | 6' 7" | 205 lbs | - |
| Esparza, Luis | RF | Free Agent | 16 | 04/14/2053 | Durango | MEX | Left | Left | 6' 6" | 195 lbs | - |
| Espinoza, Armando | SP | Motown Hitmakers | 19 | 11/07/2049 | Berriozabal | MEX | Right | Right | 6' 2" | 180 lbs | - |
| Espinoza, Carlton | CF | Free Agent | 16 | 04/12/2053 | Yabucoa | PUR | Switch | Left | 6' 5" | 185 lbs | - |
| Estrada, Andreas | SP | Great Black Swamp Mud Hens | 18 | 01/03/2051 | San Juan | PUR | Left | Left | 6' 0" | 175 lbs | - |
| Estrada, Enrique | CF | Wildwood Fishers | 22 | 01/18/2047 | Cataño | PUR | Right | Right | 6' 1" | 185 lbs | - |
| Estrada, José | 3B | Ludington LumberJacks | 30 | 01/14/2039 | Aguascalientes | MEX | Switch | Right | 6' 1" | 200 lbs | $13,500,000 |
| Estrada, Juan | CF | Great Black Swamp Mud Hens | 18 | 10/10/2050 | Tipitapa | NCA | Right | Right | 6' 3" | 190 lbs | - |
| Estradio, Luis | 1B | Madrid Jabalies | 18 | 06/09/2050 | La Romana | DOM | Right | Right | 6' 3" | 200 lbs | - |
| Ewing, Colby | RP | Ypsi Yard Cats | 22 | 08/11/2046 | Los Angeles | USA | Left | Left | 6' 2" | 185 lbs | $500,000 |
