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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saffell, Dave | 3B | Corpus Christi Hooks | 22 | 03/22/2021 | Monroe | USA | Right | Right | 6' 3" | 190 lbs | - |
| Salas, Luis | CF | Frisco RoughRiders | 23 | 10/12/2019 | Petare | VEN | Left | Left | 6' 0" | 190 lbs | - |
| Salcedo, David | RF | Arkansas Travelers | 24 | 07/04/2018 | Moa | CUB | Left | Left | 6' 2" | 200 lbs | - |
| Salinas, Juan | LF | Corpus Christi Hooks | 24 | 05/26/2019 | La Victoria | VEN | Right | Right | 6' 4" | 200 lbs | - |
| Scheer, A.J. | 3B | Corpus Christi Hooks | 25 | 02/13/2018 | Raleigh | USA | Right | Right | 6' 2" | 200 lbs | $1,260,000 |
| Schild, Josh | 2B | Wichita Wind Surge | 23 | 04/22/2020 | Chicago | USA | Right | Right | 6' 1" | 185 lbs | - |
| Segura, Bobby | SP | Free Agent | 25 | 08/08/2017 | Fort Worth | USA | Left | Right | 6' 6" | 200 lbs | - |
| Segura, Ramiro | SS | Arkansas Travelers | 24 | 10/22/2018 | Caguas | PUR | Left | Right | 6' 4" | 200 lbs | - |
| Seigler, Jerry | RP | Corpus Christi Hooks | 28 | 03/09/2015 | Wesley Hills | USA | Right | Right | 6' 4" | 205 lbs | $1,260,000 |
| Self, Jahiem | RP | Amarillo Sod Poodles | 26 | 10/22/2016 | Urbandale | USA | Switch | Right | 6' 3" | 200 lbs | - |
| Serago, Andy | RP | Arkansas Travelers | 27 | 12/30/2015 | Burbank | USA | Left | Left | 6' 3" | 200 lbs | - |
| Serrano, Arturo | SP | Free Agent | 24 | 02/26/2019 | San Pedro de Macorís | DOM | Switch | Right | 6' 0" | 180 lbs | - |
| Shadden, Mike | RP | Tulsa Drillers | 25 | 05/10/2018 | Brooks | USA | Switch | Right | 6' 6" | 205 lbs | - |
| Shalaby, Amarpreet | SP | Arkansas Travelers | 23 | 01/14/2020 | Orkney | RSA | Right | Left | 6' 1" | 185 lbs | - |
| Shannon, Mike | CF | Arkansas Travelers | 25 | 06/11/2018 | Littleton | USA | Right | Right | 6' 0" | 185 lbs | - |
| Shattock, Zachary | SP | Tulsa Drillers | 23 | 03/05/2020 | Sint Nicolas | ARU | Switch | Right | 6' 6" | 205 lbs | - |
| Shufford, Amare | SP | Amarillo Sod Poodles | 22 | 09/21/2020 | Woodland | USA | Right | Right | 6' 6" | 200 lbs | - |
| Sicairos, Juan | CF | Free Agent | 24 | 09/06/2018 | Santo Domingo | DOM | Right | Right | 6' 0" | 190 lbs | - |
| Sigalho, Macho | 2B | Free Agent | 27 | 04/30/2016 | Cabudare | VEN | Right | Right | 6' 2" | 200 lbs | - |
| Simms, Dan | 3B | Midland RockHounds | 23 | 01/12/2020 | Norman | USA | Right | Right | 6' 4" | 200 lbs | - |
| Simpson, Andy | RP | Free Agent | 28 | 10/12/2014 | Shoreview | USA | Right | Right | 6' 7" | 210 lbs | - |
| Sireus, Chris | C | Midland RockHounds | 21 | 12/29/2021 | Millbrae | USA | Left | Right | 6' 3" | 205 lbs | - |
| Sirgado, David | SP | Arkansas Travelers | 22 | 08/17/2020 | Valencia | VEN | Left | Left | 6' 1" | 190 lbs | $1,260,000 |
| Skillman, Luis | CF | Frisco RoughRiders | 24 | 10/05/2018 | University | USA | Left | Left | 6' 2" | 190 lbs | - |
| Solorio, Luis | SP | Frisco RoughRiders | 23 | 02/27/2020 | Santo Domingo | DOM | Right | Right | 6' 4" | 200 lbs | - |
| Soto, David | SP | Free Agent | 26 | 09/18/2016 | La Romana | DOM | Right | Right | 6' 2" | 200 lbs | - |
| Soto, Mike | 1B | Springfield Cardinals | 26 | 08/30/2016 | Tonawanda CDP | USA | Right | Right | 6' 2" | 210 lbs | - |
| Spadaccini, Mike | SP | Tulsa Drillers | 22 | 11/17/2020 | Chanhassen | USA | Left | Left | 6' 6" | 210 lbs | - |
| Spencer, Greg | 3B | Free Agent | 28 | 05/29/2015 | Slidell | USA | Switch | Right | 6' 1" | 195 lbs | - |
| Spencer, Josh | RP | Tulsa Drillers | 23 | 08/10/2019 | Ma'ili | USA | Switch | Right | 6' 0" | 180 lbs | - |
| Stakes, Steve | RP | Arkansas Travelers | 25 | 11/16/2017 | Grapevine | USA | Right | Right | 6' 6" | 205 lbs | - |
| Stalans, Tony | SS | Midland RockHounds | 23 | 03/20/2020 | Azusa | USA | Right | Right | 6' 0" | 175 lbs | - |
| Stall, Steve | RP | Amarillo Sod Poodles | 23 | 10/04/2019 | Easton | USA | Left | Right | 6' 6" | 200 lbs | - |
| Stalworth, Omari | CF | Midland RockHounds | 21 | 01/29/2022 | Long Beach | USA | Right | Right | 6' 0" | 175 lbs | - |
| Stanley, Rafael Josè | 1B | Corpus Christi Hooks | 25 | 09/17/2017 | Dallas | USA | Left | Left | 6' 6" | 215 lbs | - |
| Starr, Joe | RP | Northwest Arkansas Naturals | 25 | 11/26/2017 | Spring Valley | USA | Right | Right | 5' 11" | 185 lbs | - |
| Steele, Willie | SP | Corpus Christi Hooks | 23 | 09/28/2019 | Mulberry | USA | Switch | Left | 6' 2" | 195 lbs | - |
| Stewart, Jared | SS | Springfield Cardinals | 24 | 10/05/2018 | Marlborough | USA | Right | Right | 6' 2" | 185 lbs | - |
| Sturrup, Mekhi | RP | Wichita Wind Surge | 24 | 01/26/2019 | Maple Grove | USA | Right | Right | 5' 11" | 180 lbs | - |
| Suniga, Jorge | SP | Midland RockHounds | 24 | 12/30/2018 | Chitré | PAN | Left | Right | 6' 2" | 180 lbs | - |
