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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Leo | RF | Amarillo Sod Poodles | 24 | 06/10/2008 | Ixtapaluca | MEX | Left | Left | 6' 1" | 195 lbs | - |
| Salcido, Jarrod | RP | Springfield Cardinals | 26 | 06/05/2006 | Lindsay | USA | Right | Right | 6' 6" | 205 lbs | - |
| Salinas, Zayed | SP | Free Agent | 29 | 01/13/2003 | Guerrero Negro | MEX | Right | Left | 6' 0" | 165 lbs | - |
| Salvano, Mike | 3B | Midland RockHounds | 27 | 04/17/2005 | Savannah | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sandoval, Sergio | RF | Springfield Cardinals | 27 | 01/19/2005 | Randolph | USA | Left | Left | 6' 0" | 190 lbs | - |
| Santamaria, Willie | SP | Frisco RoughRiders | 25 | 01/11/2007 | Hato Mayor | DOM | Right | Right | 6' 2" | 200 lbs | - |
| Santillano, Juan | SP | Free Agent | 28 | 06/12/2004 | Maracaibo | VEN | Right | Right | 5' 10" | 180 lbs | - |
| Segui, Alden | RP | Free Agent | 30 | 10/29/2002 | Tampa | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sellers, Joe | RP | Free Agent | 31 | 09/01/2001 | Waipahu | USA | Right | Left | 6' 5" | 210 lbs | - |
| Sheppard, Carter | RP | Midland RockHounds | 31 | 09/26/2001 | Mooresville | USA | Right | Right | 6' 5" | 200 lbs | $1,200,000 |
| Shreve, Robbie | CF | Midland RockHounds | 27 | 08/19/2005 | Thousand Oaks | USA | Left | Left | 6' 2" | 200 lbs | - |
| Sierra, Robbie | C | San Antonio Missions | 22 | 02/05/2010 | Rincón | DOM | Right | Right | 6' 2" | 190 lbs | - |
| Siverling, Matthew | SP | Free Agent | 32 | 11/02/2000 | Ann Arbor | USA | Left | Left | 6' 4" | 200 lbs | - |
| Smith, Tony | C | Midland RockHounds | 25 | 03/05/2007 | New York | USA | Right | Right | 6' 0" | 200 lbs | - |
| Snook, Steven | SS | Tulsa Drillers | 29 | 08/09/2003 | Calgary | CAN | Right | Right | 6' 1" | 195 lbs | - |
| Speaker, Jacob | SP | Free Agent | 31 | 05/08/2001 | Fort Worth | USA | Right | Right | 6' 3" | 200 lbs | - |
| Spitz, Randy | 3B | Frisco RoughRiders | 27 | 01/31/2005 | Des Plaines | USA | Right | Right | 6' 0" | 185 lbs | - |
| Stalker, Geoff | RP | Arkansas Travelers | 23 | 03/11/2009 | Ridgeland | USA | Right | Right | 6' 0" | 190 lbs | - |
| Steelman, Tim | RP | Arkansas Travelers | 21 | 04/10/2011 | Boulder City | USA | Right | Right | 6' 1" | 180 lbs | - |
| Stevens, Otto | RP | Frisco RoughRiders | 27 | 02/09/2005 | Montreal | CAN | Right | Left | 6' 4" | 205 lbs | - |
| Stewart, Aerik | RP | Northwest Arkansas Naturals | 25 | 02/14/2007 | Lewisville | USA | Right | Right | 6' 1" | 205 lbs | - |
| Strever, Jim | RP | Corpus Christi Hooks | 25 | 04/04/2007 | St. Petersburg | USA | Right | Right | 5' 10" | 195 lbs | - |
| Stubblefield, Chad | 2B | Free Agent | 26 | 10/08/2006 | Fullerton | USA | Right | Right | 6' 0" | 200 lbs | - |
