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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakai, Masaharu | LF | Reno Aces | 23 | 05/01/2023 | Sanmu | JPN | Left | Right | 6' 2" | 195 lbs | - |
| Salazar, Orlando | SP | Sugar Land Skeeters | 27 | 09/22/2019 | Santo Domingo | DOM | Right | Right | 6' 3" | 200 lbs | - |
| Saldana, Andres | CF | Free Agent | 25 | 06/12/2021 | Yonkers | USA | Right | Left | 6' 2" | 195 lbs | - |
| Salgado, Ivan | 2B | Free Agent | 28 | 10/30/2018 | Champaign | USA | Right | Right | 6' 0" | 190 lbs | - |
| Salmeron, Jose | 3B | Salt Lake Bees | 24 | 07/30/2022 | Nampa | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sanchez, Gilberto | 1B | Albuquerque Isotopes | 26 | 01/24/2021 | Oakland | USA | Right | Right | 6' 1" | 200 lbs | $780,000 |
| Sanchez, Juan | SP | Free Agent | 25 | 07/01/2021 | Hazelwood | USA | Left | Right | 6' 8" | 205 lbs | - |
| Sanchez, Tony | 1B | Free Agent | 32 | 08/09/2014 | Urbandale | USA | Right | Left | 6' 2" | 200 lbs | - |
| Santizo, Ivan | 1B | Sacramento River Cats | 28 | 05/06/2018 | East Compton | USA | Left | Left | 6' 0" | 200 lbs | - |
| Sarinana, Ramon | CL | Las Vegas Aviators | 25 | 10/12/2021 | New York | USA | Switch | Right | 6' 4" | 205 lbs | - |
| Saucer, Dan | SP | Las Vegas Aviators | 24 | 01/10/2023 | Springfield | USA | Right | Right | 6' 8" | 205 lbs | - |
| Segura, Leon | 1B | Sugar Land Skeeters | 25 | 11/30/2021 | Manhattan | USA | Right | Right | 6' 3" | 200 lbs | - |
| Serna, Ramon | CF | Round Rock Express | 24 | 11/22/2022 | Brooklyn | USA | Right | Right | 6' 3" | 200 lbs | - |
| Serrano, Sergio | RP | Sugar Land Skeeters | 29 | 08/20/2017 | Tewksbury | USA | Right | Right | 6' 0" | 200 lbs | - |
| Shoemaker, Aaron | CF | Albuquerque Isotopes | 25 | 12/16/2021 | Eau Claire | USA | Left | Right | 6' 0" | 190 lbs | - |
| Silva, Tony | SP | Albuquerque Isotopes | 29 | 10/14/2017 | Covington | USA | Switch | Right | 6' 2" | 200 lbs | - |
| Silva, Victor | 1B | Reno Aces | 22 | 06/15/2024 | Caracas | VEN | Left | Left | 6' 6" | 230 lbs | - |
| Silverstein, Noe | SP | Tacoma Rainiers | 25 | 06/27/2021 | Portland | USA | Right | Right | 6' 2" | 205 lbs | - |
| Simmons, Raul | SP | Reno Aces | 23 | 08/27/2023 | Pecos | USA | Switch | Right | 6' 5" | 185 lbs | - |
| Smiley, Kyle | SS | Reno Aces | 22 | 01/16/2025 | Chicago | USA | Right | Right | 6' 2" | 190 lbs | - |
| Smith, Joe | RP | Las Vegas Aviators | 27 | 04/29/2019 | Marietta | USA | Right | Right | 6' 7" | 215 lbs | $780,000 |
| Smith, Kaden | SP | Free Agent | 28 | 03/10/2019 | Jupiter | USA | Left | Left | 6' 1" | 185 lbs | - |
| Smith, Tyler | C | Salt Lake Bees | 24 | 11/15/2022 | Brooklyn | USA | Right | Right | 5' 11" | 180 lbs | - |
| Smith, Tyler | SP | Free Agent | 32 | 10/09/2014 | Spokane | USA | Right | Right | 6' 4" | 200 lbs | - |
| Smith, Tyrese | 2B | Free Agent | 30 | 04/09/2016 | Calabasas | USA | Right | Right | 6' 1" | 200 lbs | - |
| Solano, Danny | 1B | Free Agent | 28 | 03/11/2019 | Azua | DOM | Left | Left | 6' 8" | 205 lbs | - |
| Solis, Dave | SP | Reno Aces | 24 | 02/12/2023 | Santiago | DOM | Right | Right | 6' 4" | 205 lbs | - |
| Sonnier, Mike | 2B | Albuquerque Isotopes | 20 | 12/09/2026 | Kernersville | USA | Right | Right | 6' 6" | 205 lbs | - |
| Sosa, Oscar | RP | Tacoma Rainiers | 22 | 11/05/2024 | Caucagüita | VEN | Right | Right | 6' 6" | 190 lbs | - |
| Soto, Danny | CF | Tacoma Rainiers | 23 | 04/27/2023 | Barquisimeto | VEN | Switch | Right | 5' 9" | 180 lbs | - |
| Soto, Juan | SP | Salt Lake Bees | 24 | 07/20/2022 | Falmouth | USA | Left | Left | 6' 3" | 195 lbs | $780,000 |
| Spence, Phil | 1B | Free Agent | 26 | 11/07/2020 | Montreal | CAN | Right | Right | 6' 6" | 205 lbs | - |
| Staples, Jaden | RP | Albuquerque Isotopes | 29 | 09/28/2017 | Memphis | USA | Right | Right | 6' 6" | 205 lbs | - |
| Stroman, Travis | RP | Round Rock Express | 25 | 04/14/2021 | Cleveland | USA | Right | Left | 6' 6" | 205 lbs | - |
| Suarez, Alex | 3B | Salt Lake Bees | 25 | 10/30/2021 | Fort Worth | USA | Right | Right | 6' 1" | 200 lbs | - |
