| # | Name | Team | Opp | Date | Score | AB | H | RBI | HR | R | BB | GS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jimmy Galarza | SEA | AZ | April 28, 2040 | 12-4 | 5 | 5 | 6 | 3 | 5 | 0 | 132 |
| 2 | Danny Kobelt | CHC | STL | Aug. 5, 2040 | 15-3 | 5 | 5 | 6 | 3 | 5 | 0 | 132 |
| 3 | Ignacio Razo | WSH | CIN | March 31, 2040 | 11-4 | 5 | 4 | 8 | 3 | 3 | 1 | 125 |
| 4 | Chris Vonner | COL | PHI | April 17, 2040 | 9-6 | 5 | 5 | 6 | 3 | 4 | 0 | 125 |
| 5 | Joe Robinson | BAL | CIN | May 6, 2040 | 11-2 | 5 | 5 | 4 | 2 | 5 | 0 | 113 |
| 6 | B.J. Poppino | MIA | STL | April 5, 2040 | 13-7 | 5 | 4 | 5 | 3 | 4 | 1 | 111 |
| 7 | Michael Helie | PHI | NYY | July 31, 2040 | 14-4 | 5 | 4 | 7 | 2 | 3 | 0 | 108 |
| 8 | Frank Vargas | MXC | TOR | April 24, 2040 | 8-5 | 4 | 4 | 7 | 2 | 2 | 0 | 105 |
| 9 | Willard Brulhart | BAL | NYY | Sept. 25, 2040 | 10-2 | 4 | 3 | 5 | 3 | 4 | 1 | 103 |
| 10 | Jared Jamarauli | ATL | CHC | May 24, 2040 | 12-4 | 4 | 4 | 4 | 2 | 4 | 1 | 103 |
| 11 | Alfredo Duno | LAD | TEX | June 13, 2040 | 9-4 | 3 | 3 | 7 | 2 | 2 | 1 | 102 |
| 12 | Daniel Guerra | BOS | TEX | Aug. 4, 2040 | 16-0 | 5 | 5 | 5 | 1 | 3 | 0 | 101 |
| 13 | Chad Blasingame | BAA | DET | May 11, 2040 | 12-5 | 5 | 3 | 8 | 2 | 2 | 1 | 101 |
| 14 | Danial Gandara | LAD | CLE | Sept. 8, 2040 | 19-9 | 5 | 3 | 6 | 2 | 4 | 1 | 101 |
| 15 | Ken Henry | ATL | PHI | Aug. 30, 2040 | 10-9 | 5 | 4 | 6 | 2 | 3 | 0 | 101 |
| 16 | Ernesto Polando | CHC | COL | Sept. 15, 2040 | 14-3 | 3 | 3 | 4 | 2 | 4 | 2 | 100 |
| 17 | Jesus de Loera | HOU | WSH | April 13, 2040 | 8-4 | 5 | 4 | 5 | 3 | 3 | 0 | 99 |
| 18 | Yabanne Espinoza | PHI | STL | June 1, 2040 | 9-4 | 5 | 5 | 5 | 2 | 2 | 0 | 99 |
| 19 | Brad Whitman | MIA | ATL | April 14, 2040 | 10-6 | 4 | 3 | 6 | 2 | 3 | 1 | 98 |
| 20 | Eric Compton | WSH | CAL | Aug. 12, 2040 | 11-6 | 4 | 3 | 6 | 2 | 3 | 1 | 98 |
| 21 | Resit Samim | MIN | AZ | June 28, 2040 | 19-10 | 6 | 4 | 5 | 1 | 4 | 1 | 97 |
| 22 | Grayson Crowe | BOS | CLE | April 24, 2040 | 14-5 | 4 | 4 | 3 | 1 | 4 | 2 | 96 |
| 23 | Juan Sanabria | TB | CIN | July 28, 2040 | 8-4 | 4 | 4 | 4 | 2 | 3 | 1 | 96 |
| 24 | Fradique Krusse | AZ | MIN | June 28, 2040 | 10-19 | 5 | 4 | 7 | 1 | 2 | 0 | 96 |
| 25 | Lisuarte Tendinha | HOU | MXC | May 18, 2040 | 15-10 | 6 | 4 | 5 | 3 | 3 | 0 | 95 |
| 26 | Eddie Ruise | WSH | MIA | April 27, 2040 | 7-10 | 3 | 3 | 5 | 2 | 3 | 1 | 95 |
| 27 | Eric Welborn | NYY | HOU | April 25, 2040 | 15-5 | 5 | 5 | 2 | 1 | 5 | 0 | 94 |
| 28 | Chandler Yates | PHI | CIN | April 23, 2040 | 10-8 | 5 | 4 | 5 | 2 | 3 | 0 | 94 |
| 29 | Gene High | HOU | LAD | Aug. 3, 2040 | 11-6 | 5 | 4 | 5 | 2 | 3 | 0 | 94 |
| 30 | Jestin Travis | TOR | PIT | June 2, 2040 | 7-10 | 5 | 5 | 3 | 1 | 3 | 1 | 92 |